Process Optimization Development

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Equipment Development, Design, and Optimization

The preceding is a generic description of the various factors involved in the design and development of process equipment in the process industry. Once developed, the equipment is optimized over a period of time in service to give best performance. 10.1 Case Studies in Equ ipment Design and Development

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Optimization of the tape casting process for development …

The raw materials used in the tape casting process are listed in Table 1.In our experiment, a high-purity, submicron alpha-phase alumina powder (UFPPA, purity 99.9%, d 50 =0.48 μm, a specific surface area (BET) of 15 m 2 /g, HFF-15, Fenghe Ceramics Co., Ltd., Shanghai, China) along with magnesium oxide (AR, purity 98.5%, Sinopharm Chemical …

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QbD-Guided Traditional Chinese Medicine Manufacturing Process …

Traditional methods of producing Xiaochaihu (XCH) capsules, a traditional Chinese medicine, are time-consuming, costly, and labor-intensive, which is not conductive to modernizing TCM. To address the challenges, new fluid-bed granulation and drying processes with water as the binder were developed and optimized guided by the principles of Quality by Design (QbD) …

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Systematic approach to process parameter optimization for …

In the metal additive manufacturing (AM) process of laser powder bed fusion (LPBF), there are a limited number of materials suitable for producing parts with high density and desired mechanical properties. To establish novel materials, it is essential to determine optimized process parameters in order to overcome process-related challenges and mitigate defects …

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An accelerated gradient-based optimization development …

Optimization methods are generally categorized into two categories, (i) gradient-based and (ii) non-gradient-based (Mazumdar et al., 2020).Turning to the first category, gradient-based methods, they require a continuous (or partly continuous) objective function and the gradient information for the adjustment of the step size and search direction of the optimization …

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[Development and optimization of perfusion process for …

In this paper, the unique operation and the details of process optimization for perfusion culture mode are discussed by comparing with traditional batch culture process. Meanwhile, the progress and strategies in the development and optimization of perfusion culture process in recent years are summarized to provide reference for the future ...

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Process optimization for large-scale hydrogen liquefaction

For process development and optimization, equipment technology with a high technological readiness level (TRL ≥ 7) was considered [52]. Additionally, the actual limitations in the size and performance of industrial equipment were investigated in detail and considered in the development of the new large-scale liquefaction process [27].

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Integrating multiscale modeling and optimization for …

The cornerstone of this novel approach is the multiscale modeling and optimization integration via integrating fundamentals with the power of system integration and optimization, more specifically, integrating molecular analysis, quantum chemistry and transport mechanics with process integration and mathematical optimization for clean process development.

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Multi-objective optimization of laser cladding process …

The optimization solution set is shown in Fig. 10, among which 8 sets of optimization solutions with large aspect ratios and their corresponding process parameters are shown in Table 7.Considering both cladding equipment capabilities and actual processing requirements, W/H=3.05, η=38.09%, H AR =616HV were selected as optimal solutions along ...

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Journal of Water Process Engineering

Water shortage is a fundamental challenge faced by the world in the current century. Water shortage seriously impacts the future of humanity and threatens essential ecosystem functions [1].Approximately more than a quarter of the population in the world suffers from extreme water scarcity and lack of freshwater resources [2].Water scarcity encompasses …

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Development, Optimization, and Scale-up of Process …

Chapter 33 - Development, Optimization, and Scale-up of Process Parameters: Pan Coating. Author links open overlay panel Stuart Porter, Gary Sackett, Lirong Liu. Show more. Outline. Add to Mendeley. Share. ... Process air is drawn in through an air handler where it will be heated, dehumidified (or humidified), and filtered before going to the ...

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Process Optimization

Process optimization aims to reduce cycle times and costs while improving product quality and service delivery. In manufacturing, process optimization often involves techniques such as …

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