Near Infrared Nanoparticles

A larger number of inorganic nanomaterials, such as gold nanoparticles, silver nanoparticles, carbon nanotube, graphene, iron oxide nanoparticles, and upconversion nanoparticles with excellent photothermal conversion efficacies have been used as photothermal agents [62]. Organic dye-based nanoparticles and polymer nanoparticles can also produce ...

Near-infrared II (NIR-II, 1000–1700 nm) bioimaging has been considered as one of the ideal bioimaging techniques in recent years due to its deep tissue penetration and low tissue fluorescence scattering.

In this review, we provide an at-a-glance overview of the most recent developments in near infrared nanoparticles that could have far-reaching applications in the life sciences.

Due to the unique properties of lanthanide-doped upconverting nanoparticles (UCNP) under near-infrared (NIR) light, the last decade has shown a sharp progress in their biomedicine applications. Advances in the techniques for polymer, dye, and bio-molecule conjugation on the surface of the nanoparticles has further expanded their dynamic ...

Here, an ultrasound (US) triggered near infrared‑fluorescent dinuclear iridium(III) nanoparticle, NanoIr, is first reported to precisely and spatiotemporally inhibit tumor growth. It is demonstrated that reactive oxygen species can be generated by NanoIr upon exposure to US irradiation (NanoIr + US), thereby inducing immunogenic cell death.

Development of second near-infrared (NIR-II) nanoparticles (NPs) with high biocompatibility, low toxicity, and high singlet oxygen quantum yield (Φ Δ) to prevent tumor recurrence is highly desirable in molecular imaging and photodynamic/immune combination therapy.Here, theranostic photosensitizer BODIPY (BDP)-I-N-anti-PD-L1 NPs were developed …

Assembles the state of the art heretofore appearing in scientific literature into a comprehensive, multi-perspective guidebook on near infrared-emitting nanomaterials in an assortment of biomedical applications; Explains …

Rare earth nanoparticles (RENPs) are promising NIR-responsive materials, owing to their excellent physical and chemical properties. The 4f electron subshell of lanthanides, the main group of rare earth elements, has rich energy-level …

Hence, a novel near-infrared light (NIR)-activated photosensitive drug was developed from upconversion nanoparticles (UCNPs), Pluronic F127 (F127) and curcumin (Cur) to form UCNPs-F127@Cur. This hybrid nanodrug significantly promoted the apoptosis of GSCs, increased the production of intracellular reactive oxygen species, inhibited the ...

Herein, we report near–infrared (NIR) light–cured dental restoration materials with judiciously designed upconversion nanoparticles (UCNPs) as NIR-to-UV/Vis light nanotransducers. 808 nm NIR light-driven photopolymerization of methacrylate-thiol-ene resin materials is demonstrated, a photocuring depth of more than 11 cm is obtained for the ...

Design and Spectral Characterization of the Multimodal Infrared (MMIR) Probes. To ensure more efficient O 2-sensing with the help of far-red and NIR dyes, we designed MMIR sensor probes by the nanoprecipitation technique, 71 in which the O 2-sensitive phosphorescent reporter dye, PtTPTBPF 72,73 (exc. 620 nm, em. 760 nm), and the reference O 2-insensitive …

Upconversion nanoparticles offer the potential for deep tissue biological imaging. Here, Chen et al. develop super resolution optical imaging in the near-infrared for imaging with sub-50 nm ...

Lastly, derivatives of the amphiphilic near-infrared (NIR) dye cyanine, designated C11-PC (a cyanine dye having 11 carbon chains conjugated with phosphocholine) and C11-PEG 800 (a cyanine dye having 11 carbon chains conjugated with polyethylene glycol 800) [23], were used to construct the nanoparticle mass as well as create a stable complex ...

Near-infrared light responsive gold nanoparticles coating endows polyetheretherketone with enhanced osseointegration and antibacterial properties. ... the amount of AuNPs bound to metronidazole was also relatively higher. Gold nanoparticles have been shown to be effective in promoting osteogenesis at the right concentration and size [20, 53, 54].

Here we introduce Na3CrF6, a new crystalline nanoparticle that serves as both sensitizer and host for high-brightness near-infrared emission from lanthanide activators …

Semiconducting conjugated polymer nanoparticles (SPNs) represent an emerging class of phototheranostic materials with great promise for cancer treatment. ... displays remarkable near-infrared light absorption and good photostability, as well as high photothermal conversion efficiency for photoacoustic imaging and photothermal therapy. ...

Conjugated polymers are becoming popular near-infrared II (NIR-II) phototheranostic agents (PTAs) due to their numerous advantages, such as high photostability, large molar extinction coefficients, and excellent photothermal properties. However, the strong π–π interactions between the chains of the conjugated polymers resulted in their generally low …

Moreover, the drug delivery to tumor sites and therapeutic responses could be monitored with near-infrared fluorescence using RGD-f-PNPs/EPI. This unique nanoparticle system may lead to...

Near-infrared-emitting AIE multinuclear cationic Ir(iii) complex-assembled nanoparticles for photodynamic therapy Dalton Transactions, 49 ( 2020 ), pp. 15332 - 15338 Crossref View in Scopus Google Scholar

Due to the unique properties of lanthanide-doped upconverting nanoparticles (UCNP) under near-infrared (NIR) light, the last decade has shown a sharp progress in their biomedicine applications.

Assessment of hypoxia, nutrients, metabolite gradients, and other hallmarks of the tumor microenvironment within 3D multicellular spheroid and organoid models represents a challenging analytical task. Here, we report …

This study determines whether near-infrared (NIR) light can drive tissue-penetrating cardiac optical control with upconversion luminescent materials. Adeno-associated virus (AAV) encoding channelrhodopsin-2 (ChR2) was injected intravenously to rats to achieve ChR2 expression in the heart. The upconv …

Upconversion nanoparticles (UCNPs) that emit high-energy photons upon excitation by the low-energy near-infrared (NIR) light are emerging as new optical nano-probes useful in biomedicine. Herein, we load Chlorin e6 (Ce6), a photosensitizer, on polymer-coated UCNPs, forming a UCNP-Ce6 supramolecular …

Rechargeable near-infrared persistent luminescence nanoparticles (PLNPs) were prepared first via a simple hydrothermal approach and then modified by PEGylation to improve their hydrophilicity, …

Persistent luminescence nanoparticles (PLNPs) can store energy and then achieve afterglow emission [1].PLNPs generally consist of the host, emission center, and trap [2], while the emission center achieves their characterized emission and the trap regulates the afterglow lifetime and intensity [3], [4].Thus, ions doped into the host are efficient to tune the optical properties of …

Photoacoustic (PA) imaging is advantageous for the diagnosis of superficial cancer with high spatial resolution. However, to the best of our knowledge, using an alkaline phosphatase (ALP)-activatable probe for the enhanced PA imaging of tumors has not been reported. In this work, we rationally designed a NIR probe IR775-Phe-Phe-Tyr(H2PO3)-OH …

Near-Infrared Nanoparticle-Mediated Photothermal Cancer Therapy: A Comprehensive Review of Advances in Monitoring and Controlling Thermal Effects for Effective Cancer Treatment ... nanoparticle-mediated photothermal ablation of tumors with near-infrared (NIR) light is a less invasive tool for treating cancer. This treatment is highly efficient ...

This system can exhibit enhanced near-infrared (NIR) light photocatalysis and photothermy because CDs can convert NIR light into the light of 500–600 nm and transfer electrons, which can inspire nano Au-catalyzed TNTs to generate ROS and enhance the surface plasmon resonance (SPR) effect of Au nanoparticles to produce more local photothermy ...

Introduction. Recently, cancer is the preeminent cause of mortality worldwide. 1,2 Several strategies have been implemented to treat cancer. Photodynamic therapy (PDT) has garnered widespread attention owing to its …

Near-infrared photosensitization via direct triplet energy transfer from lanthanide nanoparticles Author links open overlay panel Bingzhu Zheng 1 5, Danni Zhong 2 5, Tingting Xie 2 5, Jian Zhou 1 5, Wanlin Li 2 3, Asif Ilyas 1, Yunhao Lu 4, Min Zhou 2 3, Renren Deng 1 6